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Título: Antibacterial screening of the hypersaline cyanobacteria Aphanothece halophytica
Orientador(es): Barreira, Camila de Araujo Reveles
Moura, Laura de Andrade
Martinez, Sabrina Teixeira
Nascimento, Erika Nina do
Pereira, Marcus Rogerio Del Bel
Neves, Maria Helena Campos Baeta
Simpósio de Biotecnologia Marinha (001.:2018:Arraial do Cabo)
Palavras-chave: 579.39 22
Data do documento: 2018
Editor: IEAPM,
Descrição: Natural compounds produced by cyanobacteria have a large structural variety and several biotechnologic al applications, such as biofertilization, bioremediat ion, biofuels, food and feed. Some compounds have properties in antiviral, antibacterial, antifungal and anticancer activities. Aphano thece halophytica is a halotolerant cyanobacteria which can grow at a wide range of salt concentration and ph values. Due the adaptation strategies to live on these extreme envi ronments, they can be a rich source of bioactive co mpounds. The salt production in salines consists in the use of different water reservoirs, where natural water evaporation gradually increases salt concentration in each rese rvoir until salt precipitation. In this study, we c ollected Aphanothece halophytica strains at the crystallizer reservoir, where the s alinity was 225, at a saline in Cabo Frio, RJ. The cyanobacteria was identified by micro scopic analysis following Komarek and Anagnostidis (1988) method. Four extracts were obtained using so lvents with different polarities . The methanol extract was evaluated for antibacterial activity on micro assay s using P seudomonas sp ., Vibrio sp . and Pseudoalteromonas sp .. These bacteria are involved both in health and e nvironmental issues, due to their participation on some pathologies and on the formation of biofilms, one o f the first steps of biofouling. The extract affect ed the growth of some of the assayed bacteria with differe nt intensities, showing that it may have antibacter ial compounds. Other extractions methods and biological assays must be tested to elucidate which compounds are responsible for this activity and their mechanism o f action. These preliminary results corroborates th e biotechnological potential of cyanobacteria from hy persaline environments. The relatively low cost and fast grow of this organisms may facilitate furthers stud ies and commercial exploitation.
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